Vitamin D3+K2 Cofactor Complex 60 Capsules by Neurobiologix is a comprehensive Vitamin D support formula combining 10,000 IU of Vitamin D3 with VitaMK7 Vitamin K2 (MK-7), Boron, and Zinc Picolinate to support optimal Vitamin D cellular delivery, healthy bone mineralization, immune function, and cardiovascular function.
Key Benefits of Vitamin D3, VitaMK7 K2, Boron, and Zinc Picolinate Cofactor Ingredients
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Vitamin D3 (as Cholecalciferol, 10,000 IU / 250mcg)
- Supports immune regulation, healthy bone density, and cardiovascular function as the most bioactive and well-absorbed form of Vitamin D, sourced from lanolin in a soy-free and animal-product-free delivery
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VitaMK7 Menaquinone-7 (Vitamin K2 as MK-7, 45mcg)
- Supports healthy calcium utilization in the bloodstream and promotes osteocalcin activation, directing calcium to bone tissue and away from soft tissues through the longest-acting and most bioavailable form of Vitamin K2
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Boron (as Boron Citrate, 15mg)
- Supports Vitamin D metabolism and promotes healthy bone density, hormonal balance, and cognitive function as an essential trace mineral cofactor in Vitamin D receptor activity
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Zinc (as Zinc Picolinate, 4mg)
- Supports Vitamin D receptor function and promotes immune cell activity, antioxidant enzyme activity, and healthy cellular signaling through highly bioavailable picolinate chelation
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VDR Taq Polymorphism Support
- The inclusion of Vitamin K2 specifically addresses the VDR Taq genetic variant, which can impair cellular Vitamin D delivery unless K2 is present as a cofactor, supporting effective Vitamin D utilization regardless of genetic status
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Calcium Utilization and Bone Health Support
- VitaMK7 supports osteocalcin carboxylation and promotes healthy calcium binding to bone matrix, supporting bone density and healthy calcium metabolism
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Cardiovascular Function Support
- Vitamin K2 supports healthy vascular calcium regulation and promotes cardiovascular function by directing calcium away from arterial walls and toward bone tissue
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Immune System Support
- Vitamin D3 supports innate and adaptive immune cell function and promotes healthy immune surveillance and response through Vitamin D receptor-mediated gene expression
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Soy-Free Vitamin D3 Source
- Vitamin D3 is derived from lanolin in a soy-free process, making this formula appropriate for individuals with soy sensitivities who require high-potency Vitamin D supplementation
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Non-GMO, Solvent-Free VitaMK7
- The patented VitaMK7 K2 is processed under strict purity standards without solvents and is non-GMO, supporting a clean and high-quality K2 source
Vitamin D3+K2 Cofactor Complex is formulated around the clinical understanding that Vitamin D's effectiveness at the cellular level depends on the presence of specific cofactors, particularly Vitamin K2, Boron, and Zinc. Individuals with VDR Taq genetic polymorphisms may have impaired Vitamin D receptor function that reduces cellular Vitamin D delivery even when serum levels appear adequate, and Vitamin K2 serves as a required cofactor to support receptor activity in these individuals. The use of VitaMK7, the all-trans form of MK-7 with the highest bioavailability and longest half-life of any Vitamin K2 form, ensures that the K2 component remains active in circulation long enough to support osteocalcin carboxylation and healthy calcium utilization throughout the day from a single daily dose.
Dietary and Quality Standards
- Non-GMO
- Gluten-Free
- Soy-Free (including soy-free Vitamin D3 source)
- Dairy-Free
- VitaMK7 patented all-trans MK-7 (solvent-free)
- Lanolin-derived Vitamin D3 (soy-free)
- No artificial colors, flavors, or preservatives
- Plant-based hypromellose capsule
- Manufactured in a GMP-certified facility
- Professional-grade formula
Frequently Asked Questions
Who is Vitamin D3+K2 Cofactor Complex designed for?
Vitamin D3+K2 Cofactor Complex is formulated for adults seeking comprehensive Vitamin D support, particularly those with VDR Taq genetic polymorphisms, individuals with documented Vitamin D insufficiency, or those following protocols that require high-potency Vitamin D alongside cofactors that support cellular delivery and calcium utilization. Children and women who are pregnant or lactating should consult a healthcare practitioner before use.
How should Vitamin D3+K2 Cofactor Complex be taken?
The recommended use is 1 capsule taken daily with a meal, or as directed by a qualified healthcare practitioner. Taking with a meal that contains dietary fat supports absorption of the fat-soluble vitamins D3 and K2. Individuals taking blood-thinning medications should consider total Vitamin K intake from all sources before use and consult their healthcare provider.
Why is Vitamin K2 necessary when supplementing with high-dose Vitamin D3?
Vitamin D3 promotes calcium absorption from the intestine, increasing the amount of calcium circulating in the bloodstream. Without adequate Vitamin K2, this calcium may not be efficiently directed to bone tissue and can accumulate in soft tissues including blood vessels. Vitamin K2 activates osteocalcin and matrix Gla protein, two proteins that direct calcium to bone and support its removal from soft tissues, making K2 an important cofactor for safe and effective high-dose Vitamin D3 supplementation.
VitaMK7 is a patented form of Vitamin K2 as all-trans Menaquinone-7 (MK-7), the most bioavailable and longest-acting form of Vitamin K2. Unlike MK-4, which has a short half-life of a few hours, MK-7 remains active in circulation for 72 hours or more, supporting consistent osteocalcin activation and calcium regulation from a single daily dose. VitaMK7 is produced without solvents and is non-GMO, meeting strict purity standards.
The VDR Taq polymorphism is a genetic variant in the Vitamin D receptor gene that can impair the receptor's ability to bind and respond to Vitamin D at the cellular level. Individuals with this variant may have suboptimal Vitamin D function even when serum 25-OH Vitamin D levels appear normal. Vitamin K2 serves as a cofactor that supports Vitamin D receptor activity, and its inclusion in this formula specifically addresses the functional impairment associated with the VDR Taq variant.
Boron is a trace mineral that supports Vitamin D metabolism and promotes healthy Vitamin D receptor activity. Research indicates that Boron may support the conversion of Vitamin D to its active form and promote the retention of Vitamin D in circulation. It also supports healthy bone density, hormonal balance, and cognitive function, making it a clinically relevant addition to a comprehensive Vitamin D cofactor formula.
Does this product contain any common allergens?
Vitamin D3+K2 Cofactor Complex is formulated to be free of gluten, soy, and dairy. The Vitamin D3 is derived from lanolin using a soy-free process. It contains no artificial colors, flavors, or preservatives and uses a plant-based hypromellose capsule. Individuals taking anticoagulant medications should consult their healthcare provider before use due to the Vitamin K2 content.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
