NattoPine by NBI is a professional-grade cardiovascular and circulatory support formula designed to promote healthy blood viscosity, support normal fibrinolytic activity, and maintain healthy vascular function. This 60-capsule formula combines Nattokinase, a clinically studied enzyme derived from fermented natto, with Pine Bark Extract, a potent source of oligomeric proanthocyanidins (OPCs), to provide complementary support for healthy circulation and normal cardiovascular tissue integrity.
Key Benefits of Nattokinase, Pine Bark Extract, and Synergistic Cardiovascular Nutrients
- Nattokinase (from Bacillus subtilis natto): A serine protease enzyme derived from fermented soybean (natto) that supports healthy fibrinolytic activity, promotes normal breakdown of fibrin in the bloodstream, and maintains healthy blood viscosity and flow.
- Pine Bark Extract (Pinus pinaster, standardized for OPCs): A concentrated source of oligomeric proanthocyanidins that supports healthy endothelial function, promotes normal nitric oxide production, and maintains healthy vascular flexibility and microcirculation.
- Fibrinolytic Activity Support: Nattokinase supports the body's natural fibrinolytic system by promoting normal plasmin-like activity, helping to maintain healthy blood consistency and normal circulatory flow throughout the cardiovascular system.
- Endothelial and Vascular Function: Pine Bark OPCs support healthy nitric oxide synthase activity, promoting normal vasodilation and maintaining healthy arterial wall flexibility and endothelial integrity.
- Antioxidant Protection of Vascular Tissue: Pine Bark Extract provides potent OPC antioxidant activity, supporting healthy free radical neutralization in vascular endothelial cells and promoting normal protection of lipids from oxidative stress.
- Platelet Aggregation Balance: Both Nattokinase and Pine Bark OPCs support healthy platelet function, promoting normal platelet aggregation balance and maintaining healthy blood flow dynamics in the microcirculation.
- Microcirculation and Peripheral Circulation: Pine Bark Extract supports healthy capillary integrity and promotes normal blood flow to peripheral tissues including the extremities, eyes, and brain.
- Cardiovascular Tissue Integrity: The combined antioxidant and vascular-supportive properties of OPCs support healthy collagen and elastin cross-linking in arterial walls, promoting normal vascular structural integrity over time.
- Cognitive Circulation Support: By promoting healthy cerebral microcirculation, Pine Bark OPCs support normal cognitive function, mental clarity, and healthy oxygen delivery to neural tissue.
- Leg and Venous Circulation Comfort: Pine Bark Extract has been studied for its role in supporting healthy venous tone and promoting normal comfort in the lower extremities during prolonged sitting or standing.
- Skin Microcirculation and Collagen Support: OPCs from Pine Bark support healthy skin collagen integrity and promote normal microvascular blood flow to dermal tissue, maintaining healthy skin tone and elasticity.
- Synergistic Cardiovascular Support: The combination of Nattokinase's fibrinolytic activity with Pine Bark's endothelial and antioxidant support addresses multiple dimensions of healthy cardiovascular function that neither ingredient can provide alone.
NattoPine is built around the complementary mechanisms of two clinically studied ingredients that address cardiovascular health from different but synergistic angles. Nattokinase supports the fibrinolytic system that maintains healthy blood consistency and normal circulatory flow, while Pine Bark Extract addresses the endothelial and antioxidant dimensions of vascular health that determine how well arterial walls function and respond to oxidative stress. Together, these two ingredients provide a more comprehensive approach to healthy circulation and normal cardiovascular function than either compound alone, making NattoPine a practical option for practitioners seeking a targeted, dual-mechanism cardiovascular support formula.
Dietary & Quality Standards
- Free from wheat, gluten, milk, eggs, fish, crustacean shellfish, tree nuts, and peanuts
- Contains soy-derived Nattokinase (from fermented natto); individuals with soy allergies should consult their healthcare provider
- Pine Bark Extract standardized for oligomeric proanthocyanidin (OPC) content
- Free from artificial colors, flavors, and preservatives
- Manufactured by NBI under professional-grade quality standards
- Practitioner-formulated for clinical and integrative wellness use
Frequently Asked Questions
What is NattoPine used for?
NattoPine is a cardiovascular and circulatory support formula designed to promote healthy blood viscosity, support normal fibrinolytic activity, and maintain healthy vascular function. It is intended for adults seeking evidence-informed nutritional support for everyday cardiovascular and circulatory health under the guidance of a qualified healthcare practitioner.
How do I take NattoPine?
The recommended use is 2 capsules once per day, or as directed by a qualified healthcare practitioner. Nattokinase is generally recommended to be taken away from meals, as food may reduce its fibrinolytic activity. Consult your healthcare provider for specific timing guidance based on your individual health status and medications.
Is NattoPine safe to take with blood thinners or anticoagulant medications?
Nattokinase supports fibrinolytic activity and may have additive effects when combined with anticoagulant or antiplatelet medications such as warfarin, aspirin, clopidogrel, or newer oral anticoagulants. Individuals taking any blood-thinning medications should consult their healthcare provider before using this product. This formula should not be used as a substitute for prescribed anticoagulant therapy.
Does NattoPine contain soy?
Nattokinase is derived from Bacillus subtilis natto, a fermentation product of soybeans. While the enzyme itself is highly purified, individuals with soy allergies or sensitivities should consult their healthcare provider before use to assess whether this product is appropriate for their individual situation.
Is NattoPine safe before surgery?
Due to Nattokinase's fibrinolytic activity and Pine Bark's effects on platelet function, this product should be discontinued at least 2 weeks before any scheduled surgical procedure. Consult your surgeon and healthcare provider for specific guidance on discontinuation timing based on your individual health status and the nature of the procedure.
Can NattoPine be taken long term?
This formula is designed for ongoing daily use as part of a cardiovascular wellness regimen. For extended use beyond 90 days, or if you have a pre-existing cardiovascular condition or take prescription medications, consult a licensed healthcare provider to determine the appropriate duration and dosing for your individual needs and to monitor relevant cardiovascular markers.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
