Folic acid, the most common form of folate in supplements and fortified foods, requires the enzyme methylenetetrahydrofolate reductase (MTHFR) to be converted to L-methylfolate, the activated form of folate used by the body for many biochemical reactions. About half of the population have genetic variations that reduce the ability of the MTHFR enzyme to make this conversion. For this population, L-methylfolate supplementation is far more effective in providing this form of folate.
- Supports healthy mood, cardiovascular, and nerve function.
- Important for normal production of serotonin, norepinephrine and dopamine.
- Essential for converting homocysteine to methionine.
Frequently Asked Questions
Why might L-methylfolate be more effective than folic acid for some people?
About half of the population has genetic variations that reduce the MTHFR enzyme's ability to convert folic acid into its active form. For this population, L-methylfolate supplementation is far more effective in providing this form of folate.
What is the role of the MTHFR enzyme?
The MTHFR enzyme is required to convert folic acid into L-methylfolate. L-methylfolate is the activated form of folate used by the body for many biochemical reactions.
What bodily functions does L-methylfolate support?
It supports healthy mood, cardiovascular, and nerve function. These are among the many biochemical reactions that rely on the activated form of folate.
How does L-methylfolate relate to neurotransmitter production?
L-methylfolate is important for the normal production of serotonin, norepinephrine, and dopamine. These neurotransmitters rely on adequate levels of the activated folate form.
What role does L-methylfolate play in homocysteine metabolism?
L-methylfolate is essential for converting homocysteine to methionine. This is one of the key biochemical reactions that depend on the activated form of folate.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Suggested Use: Use as directed by a healthcare professional.
Supplement Facts:
Serving Size: 1 capsule
Servings Per Container: 90
Amount Per Serving - Daily Value (%):
Folate (5 mg folate from 6.8 mg L-5-Methylfolate, calcium salt) 8.3 mg DFE - 2,075%
Glycine 265 mg**
Other Ingredients:
Vegetarian cellulose capsule.
** Daily Value not established.
Warnings:
If you are pregnant, nursing, have a medical condition, or taking medications, consult your physician before using this product. Keep out of reach of children.
Storage:
Store in a cool, dry place.
**These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
