MegaZyme by Nature's Way is a comprehensive systemic enzyme formula designed to support the body's natural inflammatory response and promote healthy tissue recovery when taken between meals.*
Key Benefits of MegaZyme Systemic Enzymes
- Systemic Enzyme Support: Delivers a broad-spectrum blend of proteolytic enzymes that support the body's natural processes for maintaining healthy tissue and managing everyday physical stress.*
- Healthy Inflammatory Response: Promotes a balanced inflammatory response as part of normal recovery from physical activity and daily exertion.*
- Circulatory Support: Systemic enzymes support healthy blood viscosity and promote normal circulatory function throughout the body.*
- Immune System Modulation: Supports healthy immune function by promoting the body's natural ability to clear cellular debris and maintain tissue integrity.*
- Musculoskeletal Recovery: Promotes normal recovery of muscles and joints following physical activity, supporting overall mobility and comfort.*
- Digestive Enzyme Activity (when taken with meals): When taken with food, the enzyme blend also supports healthy digestion and the breakdown of proteins, fats, and carbohydrates.*
Nature's Way MegaZyme delivers a multi-enzyme complex that includes pancreatin, bromelain, papain, trypsin, and chymotrypsin — a combination of plant-based and animal-derived enzymes that work synergistically across multiple physiological systems. Unlike single-enzyme products, this broad-spectrum formula is designed to support both systemic and digestive enzyme activity depending on when it is taken — between meals for systemic support, or with meals for digestive support.* The inclusion of rutin, a bioflavonoid with antioxidant properties, further complements the formula by supporting vascular integrity and healthy circulation.*
Dietary & Quality Standards
- cGMP Compliant — manufactured in accordance with current Good Manufacturing Practices
- No Artificial Colors or Preservatives
- Enteric-Coated Tablets — designed to bypass stomach acid for optimal enzyme delivery in the small intestine
- Potency Verified — enzyme activity measured in standardized units (USP, FIP, GDU, MCU)
- Gluten Free
Frequently Asked Questions
What is MegaZyme used for?
MegaZyme is a systemic enzyme supplement used to support the body's natural inflammatory response, promote healthy tissue recovery, and maintain normal circulatory and immune function when taken between meals.*
What enzymes are in MegaZyme?
MegaZyme contains a broad-spectrum blend including pancreatin, bromelain, papain, trypsin, chymotrypsin, and rutin — each contributing to the formula's systemic and digestive enzyme activity.*
When should I take MegaZyme?
For systemic support, MegaZyme should be taken between meals on an empty stomach so the enzymes can be absorbed into the bloodstream rather than used for digestion. When taken with meals, it supports healthy digestive function instead.*
How is MegaZyme different from a regular digestive enzyme?
MegaZyme is a systemic enzyme formula, meaning it is designed to support whole-body processes — including circulation, tissue recovery, and immune function — rather than focusing solely on digestive support. Its enteric coating allows enzymes to survive stomach acid and reach the small intestine for systemic absorption.*
Is MegaZyme suitable for vegetarians?
MegaZyme contains animal-derived enzymes (pancreatin, trypsin, chymotrypsin) and is not suitable for vegetarians or vegans. Individuals with sensitivities to pork or beef-derived ingredients should consult their healthcare provider before use.
Who should consult a doctor before taking MegaZyme?
Individuals who are pregnant, nursing, taking blood-thinning medications, or scheduled for surgery should consult a qualified healthcare provider before use, as systemic enzymes may influence blood viscosity and clotting function.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Suggested Use: Two tablets before each meal.
Supplement Facts:
Serving Size: 2 Tablets
Servings Per Container: 50/ 100
Amount Per Serving | % Daily Value
Pancreatic enzymes 10X†** 325 mg
USP units of activity:
Protease 81250
Amylase 81250
Lipase 6500
Trypsin 75 mg
Papain 50 mg
Bromelain (2,400 G.D.U./g) 16 mg
Amylase 10 mg
Lipase 10 mg
Lysozyme (egg) 10 mg
Chymotrypsin 2 mg
Other ingredients: cellulose, potassium bicarbonate, modified cellulose gum, modified cellulose, magnesium stearate, soy lecithin, carnauba wax
Warnings: If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.
children. Keep out of the reach of children.
† Mega-Zyme Systemic Enzymes delivers 10 times more digestive power than the minimum activity specified by the United States Pharmacopeia.
* 325 mg of 10X are equivalent to 3,250 mg of 1X.
Storage: Store in a cool, dry location.
Dietary Considerations:
Gluten Free
*These statements have not been evaluated by the Food and Drug Administration. Information and products are meant for general use only and are not intended to diagnose, cure, treat, or prevent any disease or provide medical advice.