L-Arginine SR 350mg 60 Tablets by Endurance Products

L-Arginine SR 350mg 60 Tablets by Endurance Products delivers 350mg of L-arginine per tablet as arginine alpha-ketoglutarate in a SmartMatrix sustained-release format designed to release this conditionally essential amino acid gradually over 4 to 6 hours, supporting cardiovascular function, nitric oxide synthesis, and healthy blood flow.

Key Benefits of L-Arginine SR 350mg by Endurance Products

• Cardiovascular Function Support: L-arginine is the primary substrate for endothelial nitric oxide synthase (eNOS), the enzyme responsible for producing nitric oxide in blood vessel walls, which supports healthy vasodilation and promotes normal cardiovascular function.
• Nitric Oxide Synthesis Support: Promotes the body's natural production of nitric oxide, a signaling molecule that supports vascular tone, blood flow, and endothelial integrity throughout the circulatory system.
• Arginine Alpha-Ketoglutarate Form: Delivers L-arginine as arginine alpha-ketoglutarate (AAKG), a salt form that may support enhanced absorption and utilization compared to standard L-arginine HCl.
• SmartMatrix Sustained-Release Technology: Endurance Products Company's proprietary wax-matrix tablet releases L-arginine gradually over 4 to 6 hours, supporting more consistent plasma arginine levels and reducing the gastrointestinal discomfort sometimes associated with large single-dose arginine supplementation.
• Exercise Performance and Recovery Support: Promotes healthy blood flow to working muscles during physical activity and supports post-exercise recovery through nitric oxide-mediated vascular mechanisms.
• Immune Function Support: L-arginine is involved in immune cell proliferation and function, supporting the body's natural immune defense mechanisms at the cellular level.
• Serving Flexibility: Each serving of 3 tablets provides 1050mg of L-arginine as AAKG, with dosing frequency adjustable under healthcare professional guidance.

Why This Formula Matters

L-arginine is a conditionally essential amino acid that serves as the sole substrate for endogenous nitric oxide production via the nitric oxide synthase pathway, making adequate arginine availability central to healthy vascular tone, endothelial function, and cardiovascular support. Standard immediate-release L-arginine supplements are absorbed rapidly but may result in transient plasma peaks followed by rapid hepatic clearance, limiting the duration of elevated arginine availability for nitric oxide synthesis. Endurance Products Company's SmartMatrix sustained-release technology addresses this by extending L-arginine release over 4 to 6 hours, supporting more consistent plasma arginine levels and promoting sustained nitric oxide production throughout the day without the gastrointestinal side effects commonly reported with high single-dose arginine supplementation.

Dietary and Quality Standards

• 350mg L-arginine (as arginine alpha-ketoglutarate) per sustained-release tablet
• 1050mg L-arginine per 3-tablet serving
• SmartMatrix proprietary wax-matrix sustained-release technology
• Releases L-arginine gradually over 4 to 6 hours
• Gluten-Free
• Free from milk, egg, fish, shellfish, soy, peanuts, tree nuts, and wheat
• No salt, sugar, starch, preservatives, artificial colors, or flavorings
• 60 tablets per bottle
• Manufactured by Endurance Products Company, a US-based sustained-release tablet specialist

Frequently Asked Questions

What is L-arginine and why is it important for cardiovascular function?

L-arginine is a conditionally essential amino acid that serves as the primary substrate for nitric oxide synthase, the enzyme that produces nitric oxide in the endothelial cells lining blood vessels. Nitric oxide is a critical signaling molecule that supports healthy vasodilation, promotes normal blood flow, and maintains vascular tone throughout the circulatory system. Adequate L-arginine availability supports the body's capacity to produce nitric oxide and maintain healthy cardiovascular function.

What is arginine alpha-ketoglutarate and how does it differ from standard L-arginine?

Arginine alpha-ketoglutarate (AAKG) is a salt form of L-arginine in which the amino acid is bound to alpha-ketoglutarate, a Krebs cycle intermediate. This form may support enhanced absorption and utilization compared to standard L-arginine HCl, and is commonly used in research and clinical supplement protocols for cardiovascular and exercise performance support.

How do I take L-Arginine SR 350mg?

For adults, take three tablets twice daily, preferably with meals, or as directed by a qualified healthcare professional. Each 3-tablet serving provides 1050mg of L-arginine as arginine alpha-ketoglutarate. Do not crush or chew the sustained-release tablets, as this will disrupt the SmartMatrix delivery mechanism.

Why is a sustained-release format beneficial for L-arginine supplementation?

Standard immediate-release L-arginine is absorbed rapidly, which can result in transient plasma peaks followed by rapid hepatic clearance, limiting the duration of elevated arginine availability for nitric oxide synthesis. The SmartMatrix sustained-release format extends L-arginine release over 4 to 6 hours, supporting more consistent plasma arginine levels throughout the day and reducing the gastrointestinal discomfort sometimes associated with large single-dose arginine supplementation.

What are the other ingredients in L-Arginine SR 350mg?

Other ingredients include calcium phosphate, vegetable wax (rice bran and/or carnauba wax), stearic acid (vegetable), magnesium stearate (vegetable), and silica. The formula does not contain milk, egg, fish, shellfish, soy, peanuts, tree nuts, wheat, salt, sugar, starch, preservatives, artificial colors, or flavorings.

Who should consult a healthcare professional before use?

Individuals with a known medical condition, those taking prescription medications including medications that affect blood pressure or cardiovascular function, and pregnant or nursing women should consult a qualified healthcare professional prior to use. Keep out of reach of children.