Endur-Acin ER 500mg 100 Tablets by Endurance Products delivers 500mg of extended-release niacin (vitamin B3) per tablet using Endurance Products Company's proprietary wax-matrix sustained-release technology, designed to support healthy lipid balance, cardiovascular function, and cellular energy metabolism.
Key Benefits of Endur-Acin Extended Release Niacin 500mg
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Healthy Lipid Balance Support: Niacin supports healthy HDL cholesterol levels already within the normal range and promotes balanced lipid metabolism as part of a comprehensive cardiovascular wellness protocol.
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Cardiovascular Function Support: Promotes healthy blood flow and supports vascular function by maintaining healthy lipid profiles and supporting endothelial integrity.
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Extended-Release Delivery: Endur-Acin uses a wax-matrix tablet technology that releases niacin gradually over several hours, designed to reduce the intensity of niacin-associated skin flushing compared to immediate-release niacin formulations.
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Cellular Energy Metabolism: Niacin is a precursor to NAD+ and NADP+, coenzymes essential for mitochondrial energy production, DNA repair, and cellular redox reactions throughout the body.
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Nervous System Support: As vitamin B3, niacin supports healthy neurological function and promotes neurotransmitter synthesis pathways involved in cognitive and mood balance.
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Established Formula with Decades of Use: Endur-Acin has been manufactured by Endurance Products Company for decades, reflecting a long-standing commitment to sustained-release niacin quality and consistency.
Why This Formula Matters
Niacin is one of the most extensively studied B vitamins for cardiovascular and metabolic support, yet immediate-release niacin is widely associated with prostaglandin-mediated skin flushing that can limit tolerability and long-term compliance. Endur-Acin addresses this through a proprietary wax-matrix extended-release tablet that slows niacin absorption over time, reducing peak plasma concentrations and the associated flushing response while maintaining sustained niacin availability for metabolic and cardiovascular support. Manufactured by Endurance Products Company, a US-based company with specialized expertise in sustained-release tablet technology, Endur-Acin represents a clinically informed approach to niacin supplementation designed for individuals who require consistent, long-term B3 support.
Dietary and Quality Standards
- 500mg niacin (vitamin B3) per extended-release tablet
- Proprietary wax-matrix sustained-release tablet technology
- Designed to reduce niacin-associated flushing compared to immediate-release forms
- 100 tablets per bottle
- Gluten-Free
- No artificial colors or flavors
- Manufactured by Endurance Products Company, a US-based sustained-release tablet specialist with decades of manufacturing experience
Frequently Asked Questions
What is extended-release niacin and how does it differ from immediate-release niacin?
Extended-release niacin is formulated to release niacin gradually over several hours rather than all at once. Immediate-release niacin is absorbed rapidly, which can cause a significant rise in prostaglandin levels that triggers skin flushing, redness, and warmth, a common and often uncomfortable side effect. The extended-release format used in Endur-Acin is designed to slow this absorption, reducing peak plasma concentrations and the associated flushing response while maintaining sustained niacin availability for metabolic support.
What is the wax-matrix technology used in Endur-Acin?
Wax-matrix tablet technology involves embedding the active ingredient within a wax-based matrix that controls the rate at which the ingredient is released as the tablet passes through the gastrointestinal tract. This approach allows for a gradual, sustained release of niacin over time without the use of enteric coatings or polymer shells, and is the proprietary delivery method that Endurance Products Company has refined over decades of sustained-release tablet manufacturing.
How do I take Endur-Acin ER 500mg?
Use as directed by a qualified healthcare professional. Niacin dosing for lipid and cardiovascular support varies significantly by individual, and the appropriate dose should be determined in consultation with a licensed healthcare provider. Do not crush or chew the extended-release tablet, as this will disrupt the sustained-release mechanism.
Will I experience flushing with Endur-Acin?
The extended-release format of Endur-Acin is designed to reduce the intensity of niacin-associated flushing compared to immediate-release niacin. However, some individuals may still experience mild flushing, particularly when starting supplementation or increasing dose. Taking Endur-Acin with food and avoiding hot beverages or alcohol around the time of dosing may help further minimize this response. Consult a healthcare professional if flushing is persistent or uncomfortable.
Can I take Endur-Acin with other medications or supplements?
Niacin may interact with certain medications and supplements. Always consult a qualified healthcare professional before adding Endur-Acin to your regimen, particularly if you are currently taking prescription medications or managing a diagnosed health condition.
Who should consult a healthcare professional before use?
Pregnant or nursing women, children under 18, individuals with liver conditions, those taking prescription medications, and anyone with a history of gout or peptic ulcer should consult a qualified healthcare professional before use. Keep out of reach of children.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Suggested Use:
As a dietary supplement for adults, take one (1) to two (2) tablets, twice daily, with food. Use only as directed by your healthcare professional.
Supplement Facts:
Serving size: One Extended Release Tablet
Servings per container: 100
Amount Per Serving:
Niacin ... 500mg
(as nicotinic acid)
Other Ingredients:
Vegetable wax (rice bran and/or carnauba), stearic acid (vegetable), magnesium stearate (vegetable), and silica.
Does Not Contain:
Milk, egg, fish, shellfish, soy, peanuts, tree nuts or wheat.
Warnings:
Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking any medications, or are pregnant or nursing. Temporary flushing, itching or warming of the skin may occur. Do not use without the advice of your physician if you consume more than modest amounts of alcohol, have poorly controlled diabetes, liver disease, gout, active peptic ulcer disease, or unstable angina.
