Clear Focus by Thorne combines L-Tyrosine and a clinically studied Sage extract to support mental clarity, sustained attention, working memory, and healthy neurotransmitter balance in two daily capsules, formulated to Thorne's rigorous pharmaceutical-grade manufacturing standards.
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L-Tyrosine
- An amino acid that serves as the direct precursor to dopamine, norepinephrine, and epinephrine, the catecholamine neurotransmitters central to focus, motivation, alertness, and cognitive performance under conditions of mental demand or stress.
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Sage (Salvia officinalis)
- A clinically studied botanical with a well-documented history of use for supporting cognitive function, promoting working memory, and maintaining acetylcholine activity in the brain by supporting healthy acetylcholinesterase regulation, the enzyme responsible for breaking down acetylcholine.
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Dopamine & Norepinephrine Precursor Support
- L-Tyrosine supports the synthesis of catecholamine neurotransmitters that are foundational to executive function, sustained attention, and mental drive, particularly relevant during periods of cognitive demand, stress, or sleep disruption.
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Acetylcholine Activity Support
- Sage supports healthy acetylcholine availability in the brain, a neurotransmitter closely associated with memory consolidation, learning, and attentional performance.
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Working Memory & Cognitive Clarity
- The combination of L-Tyrosine and Sage addresses two distinct neurotransmitter systems, catecholaminergic and cholinergic, that together support the cognitive domains most relevant to focus, memory, and mental clarity.
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Stress-Resilient Cognitive Performance
- L-Tyrosine is particularly well-studied for supporting cognitive performance under conditions of acute stress, fatigue, or sleep restriction, where catecholamine depletion can impair mental function.
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Thorne Quality Assurance
- Formulated and manufactured by Thorne, a brand recognized for pharmaceutical-grade quality standards, rigorous third-party testing, and a commitment to ingredient purity and potency.
Cognitive performance depends on the coordinated activity of multiple neurotransmitter systems, and most single-ingredient cognitive support products address only one of these systems. Clear Focus targets two complementary pathways simultaneously: L-Tyrosine supports the catecholamine system (dopamine and norepinephrine) that drives alertness, motivation, and executive function, while Sage supports the cholinergic system (acetylcholine) that underlies memory consolidation and attentional precision. This dual-pathway approach is grounded in the clinical research on both ingredients, with Sage in particular having been studied in randomized controlled trials for its effects on working memory and cognitive performance in healthy adults. Together, they provide a more complete cognitive support profile than either ingredient alone.
Dietary & Quality Standards
- Non-GMO
- Gluten-Free
- Free from major allergens
- Free from artificial colors, flavors, and fillers
- Manufactured in a facility that meets NSF International Good Manufacturing Practices
- Third-party tested for purity, potency, and the absence of contaminants
- No unnecessary excipients or additives
- Suitable for daily use as part of a cognitive performance and brain health protocol
Frequently Asked Questions
Who is Clear Focus intended for?
Clear Focus is formulated for adults looking to support mental clarity, sustained attention, working memory, and healthy neurotransmitter balance as part of a daily cognitive wellness routine. It is particularly relevant for individuals with high cognitive demands, those experiencing stress-related mental fatigue, and adults focused on maintaining cognitive performance as they age. It is not intended to diagnose, treat, cure, or prevent any disease.
How should I take Clear Focus?
The recommended serving is 2 capsules once per day. Many users prefer taking it in the morning with or without food to support focus and mental clarity throughout the day. Consistent daily use is encouraged to support cumulative neurotransmitter and cognitive benefits over time.
What is L-Tyrosine and how does it support focus?
L-Tyrosine is a non-essential amino acid that the body uses to synthesize dopamine, norepinephrine, and epinephrine, the catecholamine neurotransmitters that regulate alertness, motivation, executive function, and the stress response. Under conditions of mental demand, stress, or sleep restriction, catecholamine levels can become depleted, impairing cognitive performance. L-Tyrosine supplementation supports the replenishment of these neurotransmitter precursors, promoting sustained cognitive performance under demanding conditions.
How does Sage support memory and cognitive function?
Sage (Salvia officinalis) contains bioactive compounds including rosmarinic acid and terpenoids that support healthy acetylcholinesterase regulation. Acetylcholinesterase is the enzyme that breaks down acetylcholine in the brain. By supporting healthy regulation of this enzyme, Sage promotes the availability of acetylcholine, a neurotransmitter closely associated with memory consolidation, learning, and attentional performance. Sage has been studied in randomized controlled trials in healthy adults and has demonstrated support for working memory and cognitive accuracy.
Is Clear Focus a stimulant?
Clear Focus does not contain caffeine or other stimulant compounds. L-Tyrosine supports neurotransmitter synthesis through a nutritional precursor mechanism rather than a stimulant mechanism, and Sage supports cholinergic activity through botanical enzyme regulation. The result is a formula that promotes cognitive clarity and focus without the stimulant effects or subsequent energy crashes associated with caffeine-based cognitive support products.
Can I take Clear Focus with other supplements or medications?
These ingredients are generally well-tolerated. Individuals taking medications that affect dopamine, norepinephrine, or acetylcholine activity, including certain antidepressants, thyroid medications, or medications for cognitive conditions, should consult a qualified healthcare provider before use. Those with phenylketonuria (PKU) should avoid this product due to the L-Tyrosine content.
How long before I notice results?
Individual responses vary. Some users report noticing improvements in focus and mental clarity within the first few days of consistent use, particularly from the L-Tyrosine component. Benefits related to working memory and sustained cognitive performance from Sage are typically more apparent with consistent daily use over 4 to 8 weeks.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
