B-Complex + 10 mg L-Methylfolate 30 Capsules by MethylPro delivers a comprehensive blend of bioactive B vitamins alongside a clinically relevant dose of L-methylfolate to support methylation, energy metabolism, and neurological function.
Key Benefits of B-Complex + 10 mg L-Methylfolate
-
Methylation Support
- Provides 10 mg of L-methylfolate (5-MTHF), the bioactive, end-form of folate that is immediately usable by the body without requiring enzymatic conversion
-
Energy Metabolism
- B vitamins including B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), and B6 (pyridoxine) support the conversion of macronutrients into cellular energy via the Krebs cycle
-
Nervous System Function
- Vitamins B6, B12 (methylcobalamin), and folate promote healthy neurotransmitter synthesis and neurological signaling
-
Homocysteine Metabolism
- The combination of methylfolate, methylcobalamin, and B6 supports normal homocysteine metabolism, a key marker of cardiovascular and cognitive function
-
Biotin and Cellular Health
- Biotin (B7) supports fatty acid synthesis, gene expression, and healthy metabolic function
-
Adrenal and Stress Response
- Pantothenic acid (B5) maintains adrenal function and supports the body's normal response to physiological stress
-
Red Blood Cell Formation
- Folate and B12 promote healthy red blood cell production and normal oxygen transport
MethylPro's B-Complex + 10 mg L-Methylfolate is formulated with bioavailable, coenzymated forms of B vitamins, meaning the body can utilize them directly without relying on enzymatic conversion steps that may be compromised in individuals with common genetic variants such as MTHFR polymorphisms. The inclusion of 10 mg L-methylfolate alongside methylcobalamin creates a synergistic foundation for one-carbon metabolism, which underlies DNA synthesis, neurotransmitter production, and cellular repair. This formula is designed for individuals who require targeted nutritional support for methylation pathways and sustained metabolic function.
Dietary & Quality Standards
- Non-GMO
- Gluten-Free
- Free from artificial colors, flavors, and preservatives
- Manufactured in a GMP-certified facility
- Third-party tested for purity and potency
- Suitable for vegetarians (verify capsule source with current product labeling)
Frequently Asked Questions
What is L-methylfolate and how does it differ from folic acid?
L-methylfolate (5-MTHF) is the biologically active form of folate that circulates in the bloodstream and crosses the blood-brain barrier. Unlike folic acid, which requires conversion through multiple enzymatic steps, L-methylfolate is immediately available for use in methylation reactions. Individuals with MTHFR gene variants may have reduced ability to convert folic acid, making L-methylfolate a more direct option for supporting folate-dependent pathways.
Who may benefit from a B-complex with high-dose methylfolate?
This formula may be appropriate for adults seeking support for methylation, energy metabolism, and neurological function, particularly those with increased nutritional demands, dietary gaps, or genetic variants that affect folate metabolism. As with any supplement, consultation with a qualified healthcare provider is recommended before use.
Methylcobalamin is the active, methyl-donor form of vitamin B12. It works in concert with L-methylfolate to support the methylation cycle, promote healthy homocysteine metabolism, and maintain neurological function. This form is generally considered more bioavailable than cyanocobalamin for direct cellular utilization.
How should B-Complex + 10 mg L-Methylfolate be taken?
Follow the dosage instructions on the product label or as directed by a licensed healthcare practitioner. B vitamins are water-soluble and are generally well tolerated; however, individual needs vary based on health status and nutritional requirements.
Is this product suitable for individuals following a methylation protocol?
This formula is designed to provide foundational support for methylation pathways through the inclusion of L-methylfolate, methylcobalamin, and complementary B vitamins. It is commonly used as part of a broader nutritional protocol under the guidance of a healthcare provider familiar with methylation biochemistry.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Suggested Use:
As a dietary supplement, take 1 capsule daily, or as directed by a healthcare practitioner.
Supplement Facts:
Serving Size: 1 Capsule
Servings Per Container: 30
Amount Per Serving:
Thiamine (as Thiamine Mononitrate) ... 25 mg
Riboflavin (as Riboflavin 5’ Phosphate) ... 25 mg
Niacin (as Niacinamide) ... 150 mg NE
Vitamin B6 (as Pyridoxine HCl and Pyridoxal 5’ Phosphate) ... 30 mg
Folate (10 mg from 13.9 mg L-5-Methylfolate, calcium salt) ... 16.7 mg DFE
Vitamin B12 (as Methylcobalamin) ... 1000 mcg
Biotin ... 400 mcg
Pantothenic Acid (as Calcium D-Pantothenate) ... 135 mg
Choline (as Choline Bitartrate) ... 50 mg
Inositol ... 50 mg
PABA (Para Amino Benzoic Acid) ... 50 mg
Other Ingredients:
Hydroxypropyl methylcellulose, silicon dioxide, magnesium stearate, microcrystalline cellulose, calcium silicate, rice extract blend (rice bran extract, rice hulls, gum arabic, sunflower oil)
Source Materials:
L-5-methylfolate, calcium salt: synthetic. Glycine: synthetic. Cellulose for capsules is derived from softwood tree pulp
Allergens:
According to information provided by our suppliers, these capsules are free of the nine major allergens as identified by the Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA): Wheat (gluten), eggs, milk, soybeans, shellfish, fish, peanuts, tree nuts, and sesame.
Warnings:
Pregnant or lactating women and individuals taking prescription medications should consult with a healthcare professional before taking any supplement.
