Since the late 1980s, products by Thorne Research are formulated based on clinical research and medical literature to ensure that each ingredient will contribute to the potency of the product. Thorne Research has an extensive clinical trials program for their nutritional supplements. Thorne Research has more than 40 products in clinical trials around the world.

Thorne Research partners with many independent researchers and have participated in a study with Mayo Clinic and the University of Minnesota Clinical and Translation Science Institute regarding the effect of Nicotinamide Riboside on brain NAD+ among football athletes.

Ingredients are of the highest quality and Thorne Research has a strict, clean manufacturing process and is conscious of environmental issues when manufacturing their supplements. Thorne Research believes that the higher in quality an ingredient is, the more potent, absorbent and digestible a product will be.

When formulating their products, Thorne Research also takes into consideration potential allergens and contaminants. Thorne Research test for 760 unique items, including arsenic, cadmium, mold, yeast, salmonella, e coli, lead, heavy metals, residual solvent, pesticide residue, benzopyrene and many more.

Thorne Research has their own manufacturing facilities, enabling them to be in direct control of their manufacturing process to ensure that cleanliness and quality standards are met. Thorne Research perform their final production of products in Summerville, South Carolina and are cGMP, TGA and NSF certified.