Pregnenolone Plus 60 Capsules by Neurobiologix is a targeted hormonal support formula combining 40mg of natural Pregnenolone with 75mg of Niacinamide to support healthy steroid hormone production, cognitive function, mood balance, and mitochondrial energy metabolism.
Key Benefits of Pregnenolone and Niacinamide Hormonal and Neurological Support Ingredients
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Pregnenolone (40mg per capsule)
- Supports healthy steroid hormone biosynthesis as the primary precursor pro-hormone for cortisol, DHEA, estrogen, progesterone, testosterone, and aldosterone, promoting comprehensive hormonal balance throughout the body
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Niacinamide (as Niacin, 75mg per capsule)
- Supports mitochondrial energy production through NADH conversion and promotes healthy cardiovascular function, nervous system function, and immune activity as an essential B3 cofactor in cellular metabolism
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NMDA Receptor Modulation Support
- Pregnenolone supports healthy NMDA receptor activity in the brain, promoting learning, memory consolidation, and cognitive alertness through neurosteroid signaling
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GABA Receptor Modulation Support
- Pregnenolone supports healthy GABA receptor function and promotes mood stability, relaxation, healthy sleep quality, and neurological calm through its neurosteroid activity
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Adrenal and Hormonal Axis Support
- Pregnenolone is produced primarily in the adrenal glands and supports the body's ability to maintain adequate steroid hormone levels, promoting healthy stress response and hormonal resilience
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Cognitive and Memory Support
- Pregnenolone supports healthy neurosteroid levels in the brain and promotes cognitive function, memory, and mental clarity through its modulation of key neurotransmitter receptor systems
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Mood and Sleep Support
- Through GABA receptor modulation, Pregnenolone promotes healthy mood stability and supports restful sleep quality as part of its neurosteroid activity in the central nervous system
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Mitochondrial Protection Support
- Niacinamide supports mitochondrial function and promotes cellular energy production through its role in the NAD+ pathway, complementing Pregnenolone's hormonal support with foundational cellular energy support
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Multi-Tissue Pregnenolone Production Support
- Pregnenolone is naturally produced in the adrenal glands, brain, liver, skin, gonads, and retina, and supplementation supports healthy levels across these diverse tissue compartments
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Vegetable Cellulose Capsule Delivery
- Supports a clean, plant-based delivery system free of animal-derived gelatin and common allergens
Pregnenolone Plus is formulated around the clinical understanding that Pregnenolone is the foundational precursor from which all human steroid hormones are synthesized. Without adequate Pregnenolone, the body's capacity to produce cortisol, DHEA, estrogen, progesterone, and testosterone is limited, making Pregnenolone support a foundational consideration in comprehensive hormonal wellness protocols. The inclusion of Niacinamide addresses the mitochondrial energy requirements of steroid hormone synthesis and provides independent support for cardiovascular and nervous system function, making this a dual-purpose formula that supports both the hormonal and cellular energy dimensions of overall wellness.
Dietary and Quality Standards
- Non-GMO
- Gluten-Free
- Wheat-Free
- Corn-Free
- Soy-Free
- Dairy-Free
- No artificial colors, sweeteners, or preservatives
- Vegetable cellulose capsule (plant-based)
- Rice flour capsule fill (no magnesium stearate)
- Manufactured in a GMP-certified facility
- Professional-grade formula
Frequently Asked Questions
Who is Pregnenolone Plus designed for?
Pregnenolone Plus is formulated for adults seeking support for healthy hormonal balance, cognitive function, mood stability, and mitochondrial energy production. It is particularly relevant for individuals experiencing age-related changes in steroid hormone levels or those following comprehensive hormonal wellness protocols under the guidance of a qualified healthcare practitioner.
How should Pregnenolone Plus be taken?
The recommended use is 1 capsule taken in the morning daily, or as directed by a qualified healthcare practitioner. Morning dosing aligns with the body's natural cortisol and hormonal rhythm, which peaks in the early morning hours.
What is Pregnenolone and why is it considered a foundational hormone?
Pregnenolone is a naturally occurring pro-hormone produced primarily in the adrenal glands, with smaller amounts produced in the brain, liver, skin, gonads, and retina. It is the biochemical starting point for all steroid hormone synthesis in the human body, serving as the precursor from which cortisol, DHEA, estrogen, progesterone, testosterone, and aldosterone are all derived. Supporting healthy Pregnenolone levels promotes the body's capacity to maintain adequate levels of these downstream hormones.
How does Pregnenolone support cognitive function?
Pregnenolone functions as a neurosteroid in the brain, modulating two key neurotransmitter receptor systems: NMDA receptors, which are involved in learning, memory, and alertness, and GABA receptors, which are involved in mood stability, relaxation, and sleep. By supporting healthy activity at both receptor systems, Pregnenolone promotes a balanced neurological environment that supports both cognitive performance and emotional wellness.
Niacinamide, the active form of Vitamin B3, supports mitochondrial energy production through its conversion to NADH, a coenzyme essential for cellular ATP synthesis. Steroid hormone production is an energy-intensive process that depends on healthy mitochondrial function. Including Niacinamide supports the cellular energy environment needed for optimal Pregnenolone utilization and downstream hormone synthesis, while also providing independent support for cardiovascular and nervous system function.
Is Pregnenolone appropriate for long-term use?
Pregnenolone supplementation should be guided by a qualified healthcare practitioner, particularly for long-term use, as it influences the body's hormonal cascade. Regular monitoring of hormone levels through laboratory testing is recommended to ensure appropriate dosing and to assess the body's response over time. As with any hormonal support supplement, individual needs and responses vary significantly.
Does this product contain any common allergens?
Pregnenolone Plus is formulated to be free of wheat, gluten, corn, soy, and dairy. It contains no artificial colors, sweeteners, or preservatives and uses a plant-based vegetable cellulose capsule. Individuals with specific sensitivities should review the full ingredient list and consult their healthcare provider prior to use.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
