L-Lysine 500 mg by NOW Foods provides a clinically relevant dose of this essential amino acid in a clean, vegetarian capsule, formulated to support collagen synthesis, immune function, and calcium metabolism in adults.
Key Benefits of L-Lysine
- Collagen Synthesis Support – L-Lysine is a required cofactor in the hydroxylation of proline and hydroxyproline, two amino acids critical to the structural integrity of collagen — the primary protein in skin, tendons, ligaments, and bone matrix.
- Immune System Support – Supports the normal function of immune cells and the body's natural defense mechanisms, particularly during periods of physical stress or increased nutritional demand.
- Calcium Absorption & Bone Metabolism – L-Lysine promotes intestinal calcium absorption and supports renal calcium retention, contributing to healthy bone mineral density maintenance.
- Skin Integrity & Wound Support – As a collagen precursor, L-Lysine supports the structural repair processes involved in maintaining healthy skin tissue and normal wound healing response.
- Antiviral Defense Support – L-Lysine has been studied for its role in supporting the body's natural balance of amino acids that influence certain viral replication pathways, particularly in relation to arginine metabolism.
- Protein Synthesis – As an essential amino acid, L-Lysine cannot be synthesized endogenously and must be obtained through diet or supplementation; it plays a foundational role in overall protein metabolism and nitrogen balance.
L-Lysine is classified as an essential amino acid, meaning the human body cannot produce it — adequate intake is entirely dependent on dietary sources or supplementation. NOW Foods delivers 500 mg of free-form L-Lysine per capsule, a bioavailable form that does not require enzymatic digestion prior to absorption, supporting efficient uptake across the intestinal mucosa. This formula is particularly relevant for individuals with elevated collagen turnover demands, those following low-lysine dietary patterns (e.g., high grain, low animal protein), or adults seeking targeted amino acid support without unnecessary excipients.
Dietary & Quality Standards
- Non-GMO Verified
- Gluten-Free
- Soy-Free
- Vegan/Vegetarian-Friendly (Vegetarian Capsule)
- Dairy-Free
- Egg-Free
- No Artificial Colors, Flavors, or Sweeteners
- GMP Quality Assured — manufactured in a GMP-certified facility
- Kosher & Halal Certified
Frequently Asked Questions
What is L-Lysine 500 mg used for?
L-Lysine 500 mg is formulated to support collagen production, immune function, calcium metabolism, and overall protein synthesis. It is commonly used by adults seeking to maintain connective tissue integrity, support skin health, or address dietary gaps in essential amino acid intake.
Why is L-Lysine considered an "essential" amino acid?
Essential amino acids cannot be synthesized by the human body and must be obtained through food or supplementation. L-Lysine is found primarily in animal proteins (meat, dairy, eggs) and legumes; individuals following grain-heavy or plant-based diets may have lower baseline intake and may benefit from targeted supplementation.
How does L-Lysine support collagen production?
L-Lysine acts as a structural cofactor in collagen cross-linking — it is hydroxylated by the enzyme lysyl hydroxylase (in the presence of Vitamin C) to form hydroxylysine, which stabilizes the triple-helix collagen structure. Without adequate L-Lysine, collagen formation and tissue repair processes may be compromised.
What is the relationship between L-Lysine and L-Arginine?
L-Lysine and L-Arginine compete for the same intestinal and cellular transport pathways. Research suggests that maintaining a favorable lysine-to-arginine ratio may support the body's natural management of certain amino acid-dependent biological processes. This is why L-Lysine is often studied in the context of amino acid balance and immune support.
When is the best time to take L-Lysine?
L-Lysine is best taken on an empty stomach or between meals to minimize competition with other dietary amino acids for intestinal absorption. However, if gastrointestinal sensitivity is a concern, it may be taken with a small amount of food. Always follow label directions and consult a healthcare provider for individualized guidance.
Is this product suitable for vegans?
Yes — NOW L-Lysine 500 mg is encapsulated in a vegetarian capsule and contains no animal-derived ingredients, making it appropriate for vegan and vegetarian dietary patterns.
Who may benefit most from L-Lysine supplementation?
Adults following plant-based or grain-heavy diets, individuals with elevated collagen demands (athletes, aging adults, those recovering from physical stress), and anyone seeking to address dietary gaps in essential amino acid intake may benefit most from consistent L-Lysine supplementation.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
