{"product_id":"methyl-folate-plus-90-capsules-neurobiologix","title":"Methyl Folate Plus 90 Capsules by Neurobiologix","description":"\u003cp class=\"_p_13sb5_107\"\u003e\u003cstrong\u003e\u003cspan\u003eMethyl Folate Plus 90 Capsules by Neurobiologix\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e is a targeted methylation support formula providing active folate in two bioavailable forms, 5-MTHF and folinic acid, alongside essential B vitamin cofactors designed to support neurological function, healthy homocysteine metabolism, and optimal methylation pathway activity.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 id=\"key-benefits-of-5-mthf-folinic-acid-riboflavin-5-phosphate-and-niacinamide-ingredients\" class=\"_h2_13sb5_72\"\u003e\u003cspan\u003eKey Benefits of 5-MTHF, Folinic Acid, Riboflavin-5-Phosphate, and Niacinamide Ingredients\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003e5-MTHF (L-5-Methyltetrahydrofolate, as calcium salt, 9,770 mcg DFE combined)\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003eSupports active folate delivery directly to the methylation cycle without requiring enzymatic conversion, promoting neurological function, neurotransmitter synthesis, and healthy homocysteine metabolism\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eFolinic Acid (as Folinic Acid Calcium Salt)\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003ePromotes conversion to tetrahydrofolate and supports folate availability in individuals with folate receptor autoantibodies or impaired folate transport across the blood-brain barrier\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eDual Folate Form Delivery (5-MTHF + Folinic Acid)\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003eSupports a more complete folate profile by addressing both the methylation cycle and the broader tetrahydrofolate pool, promoting comprehensive neurological and immune recovery\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eRiboflavin-5-Phosphate (Vitamin B2, 30mg)\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003eSupports MTHFR enzyme activity as a critical cofactor and promotes healthy tissue repair, immune function, and nervous system integrity\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eNiacinamide (as Niacin, 125mg)\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003eSupports mitochondrial energy production through NADH conversion and promotes healthy serotonin synthesis by sparing tryptophan for neurotransmitter production\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eBlood-Brain Barrier Folate Support\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003e5-MTHF is able to cross the blood-brain barrier and supports healthy acetylcholine synthesis, promoting cognitive function and neurological wellness\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eMTHFR Polymorphism Support\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003eProvides folate in its pre-converted, biologically active form, supporting individuals with homozygous or heterozygous MTHFR variants who have reduced capacity to convert standard folic acid\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eFolate Receptor Autoantibody (FOLR) Support\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003eFolinic acid supports an alternative folate transport pathway that may remain functional in individuals with folate receptor autoantibodies\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eCardiovascular Function Support\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003eActive folate supports healthy homocysteine metabolism, which is associated with maintaining healthy cardiovascular function\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cspan\u003e\u003cstrong\u003eNeurotransmitter Synthesis Support\u003c\/strong\u003e\u003c\/span\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003e5-MTHF supports the enzymatic reactions involved in the synthesis of serotonin, dopamine, and norepinephrine, promoting healthy mood and neurological balance\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 id=\"why-this-formula-matters\" class=\"_h2_13sb5_72\"\u003e\u003cspan\u003eWhy This Formula Matters\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"_p_13sb5_107\"\u003e\u003cspan\u003eMethyl Folate Plus addresses a fundamental limitation of standard folic acid supplementation: the requirement for enzymatic conversion to the biologically active 5-MTHF form via the MTHFR enzyme. A significant portion of the population carries MTHFR gene variants that reduce this conversion efficiency, meaning standard folic acid supplements may not adequately support methylation or neurological function in these individuals. By providing both 5-MTHF and folinic acid alongside Riboflavin-5-Phosphate, a direct MTHFR enzyme cofactor, this formula supports the methylation pathway at multiple points simultaneously, making it particularly well-suited for use within comprehensive methylation protocols that include an activating B12 cofactor.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch2 id=\"dietary-and-quality-standards\" class=\"_h2_13sb5_72\"\u003e\u003cspan\u003eDietary and Quality Standards\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul class=\"_ul_13sb5_144\"\u003e\n\u003cli\u003e\u003cspan\u003eNon-GMO\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eGluten-Free\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eWheat-Free\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCorn-Free\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSoy-Free\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eDairy-Free\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eNo artificial colors or preservatives\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eRice flour-based capsule fill (no magnesium stearate)\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePlant-based hypromellose capsule\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eManufactured in a GMP-certified facility\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eProfessional-grade formula\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2 id=\"frequently-asked-questions\" class=\"_h2_13sb5_72\"\u003e\u003cspan\u003eFrequently Asked Questions\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3 id=\"who-is-methyl-folate-plus-designed-for\" class=\"_h3_13sb5_88\"\u003e\u003cspan\u003eWho is Methyl Folate Plus designed for?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_13sb5_107\"\u003e\u003cspan\u003eMethyl Folate Plus is formulated for adults who require active folate support, particularly those with MTHFR gene variants, folate receptor autoantibodies, elevated homocysteine levels, or increased neurological folate demands. It is commonly used in methylation support protocols under the guidance of a qualified healthcare practitioner.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"how-should-methyl-folate-plus-be-taken\" class=\"_h3_13sb5_88\"\u003e\u003cspan\u003eHow should Methyl Folate Plus be taken?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_13sb5_107\"\u003e\u003cspan\u003eThe recommended use is 1 capsule twice daily, or as directed by a qualified healthcare professional. For individuals following a comprehensive methylation protocol, this product is designed to be used alongside a methylated B12 cofactor such as Methylation Complete or Methylation Pro Topical, as B12 is a required cofactor in the methylation cycle.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"what-is-the-difference-between-5-mthf-and-regular-folic-acid\" class=\"_h3_13sb5_88\"\u003e\u003cspan\u003eWhat is the difference between 5-MTHF and regular folic acid?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_13sb5_107\"\u003e\u003cspan\u003e5-MTHF is the biologically active form of folate that the body can use directly in the methylation cycle without requiring enzymatic conversion. Regular folic acid must be converted through multiple enzymatic steps, including the MTHFR enzyme, before it becomes metabolically active. Individuals with MTHFR variants or other conversion impairments may not efficiently complete this process, making active 5-MTHF a more reliable option for supporting methylation.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"why-does-this-formula-include-two-forms-of-folate\" class=\"_h3_13sb5_88\"\u003e\u003cspan\u003eWhy does this formula include two forms of folate?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_13sb5_107\"\u003e\u003cspan\u003e5-MTHF and folinic acid support folate availability through complementary pathways. 5-MTHF directly enters the methylation cycle and crosses the blood-brain barrier, while folinic acid supports the broader tetrahydrofolate pool and may remain accessible in individuals with folate receptor autoantibodies who have impaired transport of 5-MTHF into the central nervous system. Together they provide more comprehensive folate support than either form alone.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"what-is-the-role-of-riboflavin-5-phosphate-in-this-formula\" class=\"_h3_13sb5_88\"\u003e\u003cspan\u003eWhat is the role of Riboflavin-5-Phosphate in this formula?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_13sb5_107\"\u003e\u003cspan\u003eRiboflavin-5-Phosphate is the active, phosphorylated form of Vitamin B2 and serves as a direct cofactor for the MTHFR enzyme. Without adequate riboflavin, MTHFR enzyme activity is reduced even in individuals without genetic variants. Including Riboflavin-5-Phosphate supports optimal MTHFR function and promotes the overall efficiency of the methylation pathway.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"why-is-niacinamide-included-in-a-folate-formula\" class=\"_h3_13sb5_88\"\u003e\u003cspan\u003eWhy is Niacinamide included in a folate formula?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_13sb5_107\"\u003e\u003cspan\u003eNiacinamide supports mitochondrial energy production through its conversion to NADH, a coenzyme essential for cellular metabolism. It also spares tryptophan from being used for niacin synthesis, making more tryptophan available for serotonin production. This is particularly relevant in neurological support protocols where neurotransmitter balance is a clinical consideration.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"does-this-product-contain-any-common-allergens\" class=\"_h3_13sb5_88\"\u003e\u003cspan\u003eDoes this product contain any common allergens?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_13sb5_107\"\u003e\u003cspan\u003eMethyl Folate Plus is formulated to be free of wheat, gluten, corn, soy, and dairy. It contains no artificial colors or preservatives and uses a plant-based hypromellose capsule. Individuals with specific sensitivities should review the full ingredient list and consult their healthcare provider prior to use.\u003c\/span\u003e\u003c\/p\u003e","brand":"Neurobiologix","offers":[{"title":"Default Title","offer_id":53623831625912,"sku":"NEURO1015","price":42.75,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0217\/3199\/9816\/files\/Methyl_Folate_Plus_90_Capsules_by_Neurobiologix.png?v=1782404280","url":"https:\/\/blueskyvitamin.com\/products\/methyl-folate-plus-90-capsules-neurobiologix","provider":"Blue Sky Vitamin","version":"1.0","type":"link"}