{"product_id":"e-400-mixed-tocopherols-now","title":"E-400 (Mixed Tocopherols) by NOW","description":"\u003cp class=\"_p_ua7qq_109\"\u003e\u003cstrong\u003e\u003cspan\u003eE-400 (Mixed Tocopherols) by NOW\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e delivers 400 IU of natural, unesterified Vitamin E in its complete tocopherol form — providing full-spectrum fat-soluble antioxidant support that mirrors the way Vitamin E occurs naturally in food sources.\u003c\/span\u003e\u003c\/p\u003e\n\u003chr class=\"_hr_ua7qq_140\"\u003e\n\u003ch2 id=\"key-benefits-of-mixed-tocopherols-vitamin-e\" class=\"_h2_ua7qq_74\"\u003e\u003cspan\u003eKey Benefits of Mixed Tocopherols (Vitamin E)\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul class=\"_ul_ua7qq_146\"\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eFull-Spectrum Antioxidant Protection\u003c\/strong\u003e — Unlike single-form Vitamin E supplements, this formula provides all four natural tocopherol fractions — d-alpha, d-beta, d-delta, and d-gamma — delivering broad-spectrum antioxidant activity across multiple cellular environments.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eCellular Membrane Defense\u003c\/strong\u003e — As a fat-soluble antioxidant, Vitamin E integrates directly into cell membranes, where it supports protection of lipid structures from free radical-induced oxidative stress.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eImmune Function Support\u003c\/strong\u003e — Vitamin E plays a recognized role in maintaining normal immune cell function, supporting the body's natural defense mechanisms at the cellular level.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eCardiovascular Function Support\u003c\/strong\u003e — Vitamin E contributes to the maintenance of healthy vascular function by supporting the integrity of lipid-rich cell membranes within the cardiovascular system.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eSkin Health Maintenance\u003c\/strong\u003e — Vitamin E's antioxidant activity supports the structural integrity of skin cells, contributing to the maintenance of healthy skin appearance and resilience.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eUnesterified Natural Form\u003c\/strong\u003e — This formula uses unesterified d-alpha Tocopherol, the natural form of Vitamin E, which is more bioavailable than synthetic dl-alpha Tocopherol (all-rac-alpha-tocopherol) commonly found in lower-cost formulations.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003chr class=\"_hr_ua7qq_140\"\u003e\n\u003ch2 id=\"why-this-formula-matters\" class=\"_h2_ua7qq_74\"\u003e\u003cspan\u003eWhy This Formula Matters\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp class=\"_p_ua7qq_109\"\u003e\u003cspan\u003eMost single-ingredient Vitamin E supplements provide only d-alpha Tocopherol in isolation — but in nature, Vitamin E exists as a family of eight related compounds, with the four tocopherol fractions (alpha, beta, delta, gamma) each contributing distinct antioxidant activity in different tissue environments. Research suggests that gamma- and delta-tocopherols, in particular, offer complementary antioxidant mechanisms not fully replicated by alpha-tocopherol alone. By delivering all four tocopherol fractions in a single softgel, this formula more closely reflects the complete Vitamin E complex found in whole food sources, supporting a more physiologically aligned approach to fat-soluble antioxidant supplementation.\u003c\/span\u003e\u003c\/p\u003e\n\u003chr class=\"_hr_ua7qq_140\"\u003e\n\u003ch2 id=\"dietary--quality-standards\" class=\"_h2_ua7qq_74\"\u003e\u003cspan\u003eDietary \u0026amp; Quality Standards\u003c\/span\u003e\u003c\/h2\u003e\n\u003cul class=\"_ul_ua7qq_146\"\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eGluten-Free\u003c\/strong\u003e — Contains no wheat or gluten\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eFree of Common Allergens\u003c\/strong\u003e — No egg, corn, shellfish, yeast, starch, or sugar\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eNo Preservatives\u003c\/strong\u003e — Clean-label formulation with no artificial additives\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eNatural Tocopherol Form\u003c\/strong\u003e — Uses unesterified d-alpha Tocopherol (natural form), not synthetic dl-alpha\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003ecGMP Manufactured\u003c\/strong\u003e — Produced by NOW Foods under current Good Manufacturing Practices\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003e\u003cstrong\u003eNon-Heat Sensitive\u003c\/strong\u003e — Standard storage conditions apply; no refrigeration required\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cblockquote class=\"_blockquote_ua7qq_177\"\u003e\n\u003cp class=\"_p_ua7qq_109\"\u003e\u003cspan\u003e⚠️ \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003eAllergen disclosure:\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e This product \u003c\/span\u003e\u003cstrong\u003e\u003cspan\u003econtains a soy derivative\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e (from the mixed tocopherol source)\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/blockquote\u003e\n\u003chr class=\"_hr_ua7qq_140\"\u003e\n\u003ch2 id=\"frequently-asked-questions\" class=\"_h2_ua7qq_74\"\u003e\u003cspan\u003eFrequently Asked Questions\u003c\/span\u003e\u003c\/h2\u003e\n\u003ch3 id=\"what-is-the-difference-between-mixed-tocopherols-and-standard-vitamin-e\" class=\"_h3_ua7qq_90\"\u003e\u003cspan\u003eWhat is the difference between mixed tocopherols and standard Vitamin E?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_ua7qq_109\"\u003e\u003cstrong\u003e\u003cspan\u003eStandard Vitamin E supplements typically contain only d-alpha Tocopherol\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, the most studied tocopherol fraction. Mixed Tocopherol formulas additionally include d-beta, d-delta, and d-gamma Tocopherol — providing a broader spectrum of antioxidant activity that more closely mirrors the complete Vitamin E complex found in dietary sources such as nuts, seeds, and vegetable oils.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"what-does-unesterified-mean-and-why-does-it-matter\" class=\"_h3_ua7qq_90\"\u003e\u003cspan\u003eWhat does \"unesterified\" mean and why does it matter?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_ua7qq_109\"\u003e\u003cstrong\u003e\u003cspan\u003eUnesterified Vitamin E (d-alpha Tocopherol)\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e refers to the free, biologically active form of the vitamin, as opposed to esterified forms (such as d-alpha Tocopheryl Acetate or Succinate). The unesterified form is immediately bioavailable without requiring enzymatic conversion, making it the preferred form for individuals seeking direct antioxidant activity.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"is-natural-vitamin-e-more-effective-than-synthetic-vitamin-e\" class=\"_h3_ua7qq_90\"\u003e\u003cspan\u003eIs natural Vitamin E more effective than synthetic Vitamin E?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_ua7qq_109\"\u003e\u003cstrong\u003e\u003cspan\u003eNatural Vitamin E (d-alpha Tocopherol) has greater biological activity\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e than synthetic Vitamin E (dl-alpha Tocopherol). The natural form is recognized and retained by the body more efficiently, with research indicating approximately twice the bioavailability of the synthetic form at equivalent IU doses.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"does-this-product-contain-soy\" class=\"_h3_ua7qq_90\"\u003e\u003cspan\u003eDoes this product contain soy?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_ua7qq_109\"\u003e\u003cstrong\u003e\u003cspan\u003eYes — this formula contains a soy derivative\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, which is the natural source of the mixed tocopherol complex. Individuals with soy allergies or sensitivities should consult a healthcare provider before use.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"is-this-product-suitable-for-vegans\" class=\"_h3_ua7qq_90\"\u003e\u003cspan\u003eIs this product suitable for vegans?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_ua7qq_109\"\u003e\u003cstrong\u003e\u003cspan\u003eNo — E-400 uses a gelatin-based softgel capsule\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, which is derived from bovine sources. This product is not suitable for vegans or strict vegetarians. Individuals seeking a vegan Vitamin E option should look for formulations using plant-derived capsules.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"how-should-e-400-mixed-tocopherols-be-taken\" class=\"_h3_ua7qq_90\"\u003e\u003cspan\u003eHow should E-400 Mixed Tocopherols be taken?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_ua7qq_109\"\u003e\u003cstrong\u003e\u003cspan\u003eThe recommended serving is 1 softgel daily\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e, preferably taken with a meal containing dietary fat. As a fat-soluble vitamin, Vitamin E absorption is significantly enhanced when consumed alongside fat-containing foods.\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3 id=\"how-should-this-product-be-stored\" class=\"_h3_ua7qq_90\"\u003e\u003cspan\u003eHow should this product be stored?\u003c\/span\u003e\u003c\/h3\u003e\n\u003cp class=\"_p_ua7qq_109\"\u003e\u003cstrong\u003e\u003cspan\u003eStore in a cool, dry place\u003c\/span\u003e\u003c\/strong\u003e\u003cspan\u003e away from direct sunlight and moisture. No refrigeration is required. Keep out of reach of children.\u003c\/span\u003e\u003c\/p\u003e","brand":"Now","offers":[{"title":"100 Softgels","offer_id":53362974556344,"sku":"NOW10253","price":19.99,"currency_code":"USD","in_stock":true},{"title":"250 Softgels","offer_id":53362974589112,"sku":"NOW10254","price":36.79,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0217\/3199\/9816\/files\/E-400_Mixed_Tocopherols_100_softgels.png?v=1776382170","url":"https:\/\/blueskyvitamin.com\/products\/e-400-mixed-tocopherols-now","provider":"Blue Sky Vitamin","version":"1.0","type":"link"}