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D-glucarate supports Phase II glucuronidation, a primary detoxification pathway that deactivates toxins and promotes their elimination. D-glucarate plays a vital protective role for the immune system by inhibiting the beta-glucuronidase enzyme that can otherwise interfere with safe removal of steroid hormones such as estrogen. Beta-glucuronidase enzymes are active throughout the body, especially in the liver, colon, lungs, skin, bladder, breast, and prostate.
